The advancement of additive manufacturing (AM) technologies presents unprecedented opportunities for the fabrication of lightweight aerospace components with complex geometries, enhanced structural performance, and significant material efficiency. However, existing studies often face critical limitations related to narrow material applicability, robotic control complexities, extensive post-processing requirements, scalability challenges, and certification constraints for aerospace deployment. In this study, an advanced additive manufacturing strategy is proposed to comprehensively address these challenges by integrating multi-material deposition, topology optimization, real-time process monitoring, adaptive robotic control, and standardization frameworks aligned with aerospace regulatory standards. The proposed framework enables superior weight reduction while maintaining mechanical integrity, reduces manufacturing lead time, minimizes assembly complexity, and improves overall production scalability. Extensive experimental validations demonstrate enhanced strength-to-weight ratios, geometric accuracy, and process reliability. This integrated approach offers a transformative pathway for industrial-scale adoption of AM in aerospace manufacturing, contributing to next-generation high-performance, cost effective, and regulation-compliant aerospace structures.